A perfect stimuli-responsive magnetic nanocomposite for intracellular delivery of doxorubicin
نویسندگان
چکیده
منابع مشابه
Polymeric composite membranes for temperature and pH-responsive delivery of doxorubicin hydrochloride
Objective(s): Nowadays hydrogels are one of the upcoming classes of polymer-based controlled-release drug delivery systems. Temperature and pH-responsive delivery systems have drawn much attention because some diseases reveal themselves by a change in temperature and/or pH. The objective of this work is to prepare and characterize composite membrane using responsive nanoparticles into a polymer...
متن کاملStimuli-responsive Hydrogel for Drug Delivery
Introduction Hydrogels have been extensively investigated as drug delivery carriers in biomedical applications.The stimuli-responsive hydrogel is generally created when an ionic monomer is incorporated into the hydrogel network, in which the charged group is formed and called fixed charge since its mobility is much less than that of freely mobile ions within the interstitial fluid. In this stud...
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Objective(s): Development of an oral sustained-controlled release vehicle which, slowly releases the drug and maintains an effective drug concentration for a long time is aimed.Materials and Methods: A biodegradable magnetic polymeric drug delivery vehicle, using superparamagnetic iron oxide nanoparticles encapsulating by polyvinylpyrrolidone-block-polyethylene glycol-block-poly methacrylic aci...
متن کاملpH-responsive charge-reversal polymer-functionalized boron nitride nanospheres for intracellular doxorubicin delivery
Background Anticancer drug-delivery systems (DDSs) capable of responding to the physiological stimuli and efficiently releasing drugs inside tumor cells are highly desirable for effective cancer therapy. Herein, pH-responsive, charge-reversal poly(allylamine hydrochlorid)-citraconic anhydride (PAH-cit) functionalized boron nitride nanospheres (BNNS) were fabricated and used as a carrier for the...
متن کاملRedox-responsive nanocapsules for intracellular protein delivery.
Direct delivery of proteins to the cytosol of cells holds tremendous potential in biological and medical applications. Engineering vehicles for escorting proteins to the cytosol in a controlled release fashion has thus generated considerable interest. We report here the preparation of redox-responsive single-protein nanocapsules for intracellular protein delivery. Through in situ interfacial po...
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ژورنال
عنوان ژورنال: Artificial Cells, Nanomedicine, and Biotechnology
سال: 2018
ISSN: 2169-1401,2169-141X
DOI: 10.1080/21691401.2018.1518911